E-Bibliothek Gesundheitskompetenz des DNGK
Autorinnenseite: Marion Danner (Mitglied des DNGK)
Hier finden Sie die in der Datenbank des DNGK eingestellten Publikationen des genannten DNGK-Mitglieds.
6298796
7ZDA33V6
1
chicago-fullnote-bibliography
50
date
title
10246
https://gesundheitskompetenz.online/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%224VCSHCE8%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Scheibler%20et%20al.%22%2C%22parsedDate%22%3A%222023-11-24%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BScheibler%2C%20F%26%23xFC%3Bl%26%23xF6%3Bp%2C%20Friedemann%20Geiger%2C%20Kai%20Wehkamp%2C%20Marion%20Danner%2C%20Marie%20Debrouwere%2C%20Constanze%20Stolz-Klingenberg%2C%20Anja%20Schuldt-Joswig%2C%20et%20al.%20%26%23x201C%3BPatient-Reported%20Effects%20of%20Hospital-Wide%20Implementation%20of%20Shared%20Decision-Making%20at%20a%20University%20Medical%20Centre%20in%20Germany%3A%20A%20Pre-Post%20Trial.%26%23x201D%3B%20%26lt%3Bi%26gt%3BBMJ%20Evidence-Based%20Medicine%26lt%3B%5C%2Fi%26gt%3B%2C%20November%2024%2C%202023%2C%20bmjebm-2023-112462.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjebm-2023-112462%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjebm-2023-112462%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Patient-reported%20effects%20of%20hospital-wide%20implementation%20of%20shared%20decision-making%20at%20a%20university%20medical%20centre%20in%20Germany%3A%20a%20pre-post%20trial%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F%5Cu00fcl%5Cu00f6p%22%2C%22lastName%22%3A%22Scheibler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friedemann%22%2C%22lastName%22%3A%22Geiger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22Wehkamp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Debrouwere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Constanze%22%2C%22lastName%22%3A%22Stolz-Klingenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Schuldt-Joswig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christina%20Gesine%22%2C%22lastName%22%3A%22Sommer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olga%22%2C%22lastName%22%3A%22Kopeleva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claudia%22%2C%22lastName%22%3A%22B%5Cu00fcnzen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Wagner-Ullrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gerhard%22%2C%22lastName%22%3A%22Koch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Coors%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Felix%22%2C%22lastName%22%3A%22Wehking%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marla%22%2C%22lastName%22%3A%22Clayman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Weymayr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leonie%22%2C%22lastName%22%3A%22Sundmacher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%20Ulrich%22%2C%22lastName%22%3A%22R%5Cu00fcffer%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20To%20evaluate%20the%20feasibility%20and%20effectiveness%20of%20the%20SHARE%20TO%20CARE%20%28S2C%29%20programme%2C%20a%20complex%20intervention%20designed%20for%20hospital-wide%20implementation%20of%20shared%20decision-making%20%28SDM%29.%5CnDESIGN%3A%20Pre-post%20study.%5CnSETTING%3A%20University%20Hospital%20Schleswig-Holstein%20%28UKSH%29%2C%20Kiel%20Campus.%5CnPARTICIPANTS%3A%20Healthcare%20professionals%20as%20well%20as%20inpatients%20and%20outpatients%20from%2022%20departments%20of%20the%20Kiel%20Campus%20of%20UKSH.%5CnINTERVENTIONS%3A%20The%20S2C%20programme%20is%20a%20comprehensive%20implementation%20strategy%20including%20four%20core%20modules%3A%20%281%29%20physician%20training%2C%20%282%29%20SDM%20support%20training%20for%20and%20support%20by%20nurses%20as%20decision%20coaches%2C%20%283%29%20patient%20activation%20and%20%284%29%20evidence-based%20patient%20decision%20aid%20development%20and%20integration%20into%20patient%20pathways.%20After%20full%20implementation%2C%20departments%20received%20the%20S2C%20certificate.%5CnMAIN%20OUTCOME%20MEASURES%3A%20In%20this%20paper%2C%20we%20report%20on%20the%20feasibility%20and%20effectiveness%20outcomes%20of%20the%20implementation.%20Feasibility%20was%20judged%20by%20the%20degree%20of%20implementation%20of%20the%20four%20modules%20of%20the%20programme.%20Outcome%20measures%20for%20effectiveness%20are%20patient-reported%20experience%20measures%20%28PREMs%29.%20The%20primary%20outcome%20measure%20for%20effectiveness%20is%20the%20Patient%20Decision%20Making%20subscale%20of%20the%20Perceived%20Involvement%20in%20Care%20Scale%20%28PICSPDM%29.%20Pre-post%20comparisons%20were%20done%20using%20t-tests.%5CnRESULTS%3A%20The%20implementation%20of%20the%20four%20components%20of%20the%20S2C%20programme%20was%20able%20to%20be%20completed%20in%2018%20of%20the%2022%20included%20departments%20within%20the%20time%20frame%20of%20the%20study.%20After%20completion%20of%20implementation%2C%20PICSPDM%20showed%20a%20statistically%20significant%20difference%20%28p%26lt%3B0.01%29%20between%20the%20means%20compared%20with%20baseline.%20This%20difference%20corresponds%20to%20a%20small%20to%20medium%20yet%20clinically%20meaningful%20positive%20effect%20%28Hedges%26%23039%3B%20g%3D0.2%29.%20Consistent%20with%20this%2C%20the%20secondary%20PREMs%20%28Preparation%20for%20Decision%20Making%20and%20collaboRATE%29%20also%20showed%20statistically%20significant%2C%20clinically%20meaningful%20positive%20effects.%5CnCONCLUSIONS%3A%20The%20hospital-wide%20implementation%20of%20SDM%20with%20the%20S2C-programme%20proved%20to%20be%20feasible%20and%20effective%20within%20the%20time%20frame%20of%20the%20project.%20The%20German%20Federal%20Joint%20Committee%20has%20recommended%20to%20make%20the%20Kiel%20model%20of%20SDM%20a%20national%20standard%20of%20care.%22%2C%22date%22%3A%222023-11-24%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1136%5C%2Fbmjebm-2023-112462%22%2C%22ISSN%22%3A%222515-4478%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%223L4EXKAR%22%2C%22Z33C2TVZ%22%2C%22J987ELTY%22%2C%22SPWXRLZV%22%2C%226DCTQ3Z4%22%2C%227ZDA33V6%22%2C%22QXIGN3AI%22%2C%22BEQ38XPW%22%2C%22P9CVNWVH%22%2C%22ERQ322N6%22%5D%2C%22dateModified%22%3A%222024-03-11T12%3A05%3A06Z%22%7D%7D%2C%7B%22key%22%3A%2229935MWJ%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Danner%20et%20al.%22%2C%22parsedDate%22%3A%222022-02-17%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDanner%2C%20Marion%2C%20Marie%20Debrouwere%2C%20Anne%20Rummer%2C%20Kai%20Wehkamp%2C%20Jens%20Ulrich%20R%5Cu00fcffer%2C%20Friedemann%20Geiger%2C%20Robert%20Wolff%2C%20Karoline%20Weik%2C%20and%20Fueloep%20Scheibler.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12911-022-01777-x%26%23039%3B%26gt%3BA%20scattered%20landscape%3A%20assessment%20of%20the%20evidence%20base%20for%2071%20patient%20decision%20aids%20developed%20in%20a%20hospital%20setting%26lt%3B%5C%2Fa%26gt%3B.%26quot%3B%20%26lt%3Bi%26gt%3BBMC%20Medical%20Informatics%20and%20Decision%20Making%26lt%3B%5C%2Fi%26gt%3B%2022%2C%20no.%201%20%28February%2017%2C%202022%29%3A%2044.%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20scattered%20landscape%3A%20assessment%20of%20the%20evidence%20base%20for%2071%20patient%20decision%20aids%20developed%20in%20a%20hospital%20setting%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Debrouwere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Rummer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22Wehkamp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%20Ulrich%22%2C%22lastName%22%3A%22R%5Cu00fcffer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friedemann%22%2C%22lastName%22%3A%22Geiger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Wolff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karoline%22%2C%22lastName%22%3A%22Weik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fueloep%22%2C%22lastName%22%3A%22Scheibler%22%7D%5D%2C%22abstractNote%22%3A%22Recent%20publications%20reveal%20shortcomings%20in%20evidence%20review%20and%20summarization%20methods%20for%20patient%20decision%20aids.%20In%20the%20large-scale%20%5Cu201cShare%20to%20Care%20%28S2C%29%5Cu201d%20Shared%20Decision%20Making%20%28SDM%29%20project%20at%20the%20University%20Hospital%20Kiel%2C%20Germany%2C%20one%20of%204%20SDM%20interventions%20was%20to%20develop%20up%20to%2080%20decision%20aids%20for%20patients.%20Best%20available%20evidence%20on%20the%20treatments%5Cu2019%20impact%20on%20patient-relevant%20outcomes%20was%20systematically%20appraised%20to%20feed%20this%20information%20into%20the%20decision%20aids.%20Aims%20of%20this%20paper%20were%20to%20%281%29%20describe%20how%20PtDAs%20are%20developed%20and%20how%20S2C%20evidence%20reviews%20for%20each%20PtDA%20are%20conducted%2C%20%282%29%20appraise%20the%20quality%20of%20the%20best%20available%20evidence%20identified%20and%20%283%29%20identify%20challenges%20associated%20with%20identified%20evidence.%22%2C%22date%22%3A%222022-02-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12911-022-01777-x%22%2C%22ISSN%22%3A%221472-6947%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12911-022-01777-x%22%2C%22collections%22%3A%5B%22ZFT52UPQ%22%2C%2246NNKHWR%22%2C%223L4EXKAR%22%2C%22J987ELTY%22%2C%22DCC2W2YR%22%2C%227ZDA33V6%22%2C%22P9CVNWVH%22%2C%22N24UXA6K%22%5D%2C%22dateModified%22%3A%222024-06-05T08%3A50%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22B5RSHYH2%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Swift%20et%20al.%22%2C%22parsedDate%22%3A%222021-12-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BSwift%2C%20Stephanie%20Louise%2C%20Thomas%20Puehler%2C%20Kate%20Misso%2C%20Shona%20Helen%20Lang%2C%20Carol%20Forbes%2C%20Jos%20Kleijnen%2C%20Marion%20Danner%2C%20et%20al.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fbmjopen.bmj.com%5C%2Fcontent%5C%2F11%5C%2F12%5C%2Fe054222%26%23039%3B%26gt%3BTranscatheter%20aortic%20valve%20implantation%20versus%20surgical%20aortic%20valve%20replacement%20in%20patients%20with%20severe%20aortic%20stenosis%3A%20a%20systematic%20review%20and%20meta-analysis%26lt%3B%5C%2Fa%26gt%3B.%26quot%3B%20%26lt%3Bi%26gt%3BBMJ%20Open%26lt%3B%5C%2Fi%26gt%3B%2011%2C%20no.%2012%20%28December%201%2C%202021%29%3A%20e054222.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2021-054222.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Transcatheter%20aortic%20valve%20implantation%20versus%20surgical%20aortic%20valve%20replacement%20in%20patients%20with%20severe%20aortic%20stenosis%3A%20a%20systematic%20review%20and%20meta-analysis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%20Louise%22%2C%22lastName%22%3A%22Swift%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Puehler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kate%22%2C%22lastName%22%3A%22Misso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shona%20Helen%22%2C%22lastName%22%3A%22Lang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carol%22%2C%22lastName%22%3A%22Forbes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jos%22%2C%22lastName%22%3A%22Kleijnen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Kuhn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Assad%22%2C%22lastName%22%3A%22Haneya%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hatim%22%2C%22lastName%22%3A%22Seoudy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jochen%22%2C%22lastName%22%3A%22Cremer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norbert%22%2C%22lastName%22%3A%22Frey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Georg%22%2C%22lastName%22%3A%22Lutter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Wolff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fueloep%22%2C%22lastName%22%3A%22Scheibler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22Wehkamp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Derk%22%2C%22lastName%22%3A%22Frank%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%20Patients%20undergoing%20surgery%20for%20severe%20aortic%20stenosis%20%28SAS%29%20can%20be%20treated%20with%20either%20transcatheter%20aortic%20valve%20implantation%20%28TAVI%29%20or%20surgical%20aortic%20valve%20replacement%20%28SAVR%29.%20The%20choice%20of%20procedure%20depends%20on%20several%20factors%2C%20including%20the%20clinical%20judgement%20of%20the%20heart%20team%20and%20patient%20preferences%2C%20which%20are%20captured%20by%20actively%20informing%20and%20involving%20patients%20in%20a%20process%20of%20shared%20decision%20making%20%28SDM%29.%20We%20synthesised%20the%20most%20up-to-date%20and%20accessible%20evidence%20on%20the%20benefits%20and%20risks%20that%20may%20be%20associated%20with%20TAVI%20versus%20SAVR%20to%20support%20SDM%20in%20this%20highly%20personalised%20decision-making%20process.%5CnDesign%20Systematic%20review%20and%20meta-analysis.%5CnData%20sources%20MEDLINE%20%28Ovid%29%2C%20Embase%20%28Ovid%29%20and%20the%20Cochrane%20Central%20Register%20of%20Controlled%20Trials%20%28CENTRAL%3B%20Wiley%29%20were%20searched%20from%20January%202000%20to%20August%202020%20with%20no%20language%20restrictions.%20Reference%20lists%20of%20included%20studies%20were%20searched%20to%20identify%20additional%20studies.%5CnEligibility%20criteria%20Randomised%20controlled%20trials%20%28RCTs%29%20that%20compared%20TAVI%20versus%20SAVR%20in%20patients%20with%20SAS%20and%20reported%20on%20all-cause%20or%20cardiovascular%20mortality%2C%20length%20of%20stay%20in%20intensive%20care%20unit%20or%20hospital%2C%20valve%20durability%2C%20rehospitalisation%5C%2Freintervention%2C%20stroke%20%28any%20stroke%20or%20major%5C%2Fdisabling%20stroke%29%2C%20myocardial%20infarction%2C%20major%20vascular%20complications%2C%20major%20bleeding%2C%20permanent%20pacemaker%20%28PPM%29%20implantation%2C%20new-onset%20or%20worsening%20atrial%20fibrillation%20%28NOW-AF%29%2C%20endocarditis%2C%20acute%20kidney%20injury%20%28AKI%29%2C%20recovery%20time%20or%20pain%20were%20included.%5CnData%20extraction%20and%20synthesis%20Two%20independent%20reviewers%20were%20involved%20in%20data%20extraction%20and%20risk%20of%20bias%20%28ROB%29%20assessment%20using%20the%20Cochrane%20tool%20%28one%20reviewer%20extracted%5C%2Fassessed%20the%20data%2C%20and%20the%20second%20reviewer%20checked%20it%29.%20Dichotomous%20data%20were%20pooled%20using%20the%20Mantel-Haenszel%20method%20with%20random-effects%20to%20generate%20a%20risk%20ratio%20%28RR%29%20with%2095%25%20CI.%20Continuous%20data%20were%20pooled%20using%20the%20inverse-variance%20method%20with%20random-effects%20and%20expressed%20as%20a%20mean%20difference%20%28MD%29%20with%2095%25%20CI.%20Heterogeneity%20was%20assessed%20using%20the%20I2%20statistic.%5CnResults%208969%20records%20were%20retrieved%20and%20nine%20RCTs%20%2861%20records%29%20were%20ultimately%20included%20%28n%3D8818%20participants%29.%20Two%20RCTs%20recruited%20high-risk%20patients%2C%20two%20RCTs%20recruited%20intermediate-risk%20patients%2C%20two%20RCTs%20recruited%20low-risk%20patients%2C%20one%20RCT%20recruited%20high-risk%20%28%5Cu226570%20years%29%20or%20any-risk%20%28%5Cu226580%20years%29%20patients%3B%20and%20two%20RCTs%20recruited%20all-risk%20or%20%5Cu2018operable%5Cu2019%20patients.%20While%20there%20was%20no%20overall%20change%20in%20the%20risk%20of%20dying%20from%20any%20cause%20%2830%20day%3A%20RR%200.89%2C%2095%25%20CI%200.65%20to%201.22%3B%20%5Cu22641%20year%3A%20RR%200.90%2C%2095%25%20CI%200.79%20to%201.03%3B%205%20years%3A%20RR%201.09%2C%2095%25%20CI%200.98%20to%201.22%29%2C%20cardiovascular%20mortality%20%2830%20day%3A%20RR%201.03%2C%2095%25%20CI%200.77%20to%201.39%3B%20%5Cu22641%20year%3A%20RR%200.90%2C%2095%25%20CI%200.76%20to%201.06%3B%202%20years%3A%20RR%200.96%2C%2095%25%20CI%200.83%20to%201.12%29%2C%20or%20any%20type%20of%20stroke%20%2830%20day%3A%20RR%200.83%2C%2095%25%20CI%200.61%20to%201.14%3B%5Cu22641%20year%3A%20RR%200.94%2C%2095%25%20CI%200.72%20to%201.23%3B%205%20years%3A%20RR%201.07%2C%2095%25%20CI%200.88%20to%201.30%29%2C%20the%20risk%20of%20several%20clinical%20outcomes%20was%20significantly%20decreased%20%28major%20bleeding%2C%20AKI%2C%20NOW-AF%29%20or%20significantly%20increased%20%28major%20vascular%20complications%2C%20PPM%20implantation%29%20for%20TAVI%20vs%20SAVR.%20TAVI%20was%20associated%20with%20a%20significantly%20shorter%20hospital%20stay%20vs%20SAVR%20%28MD%20%5Cu22123.08%20days%2C%2095%25%20CI%20%5Cu22124.86%20to%20%5Cu22121.29%3B%204%20RCTs%2C%20n%3D2758%20participants%29.%20Subgroup%20analysis%20generally%20favoured%20TAVI%20patients%20receiving%20implantation%20via%20the%20transfemoral%20%28TF%29%20route%20%28vs%20non-TF%29%3B%20receiving%20a%20balloon-expandable%20%28vs%20self-expanding%29%20valve%3B%20and%20those%20at%20low-intermediate%20risk%20%28vs%20high%20risk%29.%20All%20RCTs%20were%20rated%20at%20high%20ROB%2C%20predominantly%20due%20to%20lack%20of%20blinding%20and%20selective%20reporting.%5CnConclusions%20No%20overall%20change%20in%20the%20risk%20of%20death%20from%20any%20cause%20or%20cardiovascular%20mortality%20was%20identified%20but%2095%25%20CIs%20were%20often%20wide%2C%20indicating%20uncertainty.%20TAVI%20may%20reduce%20the%20risk%20of%20certain%20side%20effects%20while%20SAVR%20may%20reduce%20the%20risk%20of%20others.%20Most%20long-term%20%285-year%29%20results%20are%20limited%20to%20older%20patients%20at%20high%20surgical%20risk%20%28ie%2C%20early%20trials%29%2C%20therefore%20more%20data%20are%20required%20for%20low%20risk%20populations.%20Ultimately%2C%20neither%20surgical%20technique%20was%20considered%20dominant%2C%20and%20these%20results%20suggest%20that%20every%20patient%20with%20SAS%20should%20be%20individually%20engaged%20in%20SDM%20to%20make%20evidence-based%2C%20personalised%20decisions%20around%20their%20care%20based%20on%20the%20various%20benefits%20and%20risks%20associated%20with%20each%20treatment.%5CnPROSPERO%20registration%20number%20CRD42019138171.%22%2C%22date%22%3A%222021%5C%2F12%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1136%5C%2Fbmjopen-2021-054222%22%2C%22ISSN%22%3A%222044-6055%2C%202044-6055%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fbmjopen.bmj.com%5C%2Fcontent%5C%2F11%5C%2F12%5C%2Fe054222%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%223L4EXKAR%22%2C%22SPWXRLZV%22%2C%227ZDA33V6%22%2C%22QXIGN3AI%22%2C%228B2HH96K%22%2C%22BEQ38XPW%22%2C%22ACPQBWRE%22%5D%2C%22dateModified%22%3A%222024-06-06T11%3A12%3A24Z%22%7D%7D%2C%7B%22key%22%3A%22XC9Q3DJ2%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Debrouwere%20et%20al.%22%2C%22parsedDate%22%3A%222021-02-23%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDebrouwere%2C%20Marie%2C%20Anne%20Rummer%2C%20Divna%20Tafelski%2C%20Corinna%20Knauff%2C%20Friedemann%20Geiger%2C%20Kai%20Wehkamp%2C%20Ulrich%20R%26%23xFC%3Bffer%2C%20F%26%23xFC%3Bl%26%23xF6%3Bp%20Scheibler%2C%20and%20Marion%20Danner.%20%26%23x201C%3BWie%20gut%20ist%20die%20Studienlage%20f%26%23xFC%3Br%20wichtige%20Behandlungsentscheidungen%20im%20Krankenhaus%3F%2C%26%23x201D%3B%20Doc21ebmPS-4%26%23x2013%3B10.%20German%20Medical%20Science%20GMS%20Publishing%20House%2C%202021.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3205%5C%2F21ebm081%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3205%5C%2F21ebm081%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22conferencePaper%22%2C%22title%22%3A%22Wie%20gut%20ist%20die%20Studienlage%20f%5Cu00fcr%20wichtige%20Behandlungsentscheidungen%20im%20Krankenhaus%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Debrouwere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Rummer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Divna%22%2C%22lastName%22%3A%22Tafelski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Corinna%22%2C%22lastName%22%3A%22Knauff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friedemann%22%2C%22lastName%22%3A%22Geiger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22Wehkamp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22R%5Cu00fcffer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F%5Cu00fcl%5Cu00f6p%22%2C%22lastName%22%3A%22Scheibler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021-02-23%22%2C%22proceedingsTitle%22%3A%22%22%2C%22conferenceName%22%3A%22%22%2C%22language%22%3A%22germ%22%2C%22DOI%22%3A%2210.3205%5C%2F21ebm081%22%2C%22ISBN%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%223L4EXKAR%22%2C%22J987ELTY%22%2C%22SPWXRLZV%22%2C%22DCC2W2YR%22%2C%227ZDA33V6%22%2C%22QXIGN3AI%22%2C%22BEQ38XPW%22%5D%2C%22dateModified%22%3A%222024-03-11T11%3A55%3A11Z%22%7D%7D%2C%7B%22key%22%3A%22WKUTWUN4%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Koldehoff%20et%20al.%22%2C%22parsedDate%22%3A%222021-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BKoldehoff%2C%20Andreas%2C%20Marion%20Danner%2C%20Daniele%20Civello%2C%20Kerstin%20Rhiem%2C%20Stephanie%20Stock%2C%20and%20Dirk%20M%5Cu00fcller.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fpubmed.ncbi.nlm.nih.gov%5C%2F33518037%5C%2F%26%23039%3B%26gt%3BCost-Effectiveness%20of%20Targeted%20Genetic%20Testing%20for%20Breast%20and%20Ovarian%20Cancer%3A%20A%20Systematic%20Review%26lt%3B%5C%2Fa%26gt%3B.%26quot%3B%20%26lt%3Bi%26gt%3BValue%20in%20Health%3A%20The%20Journal%20of%20the%20International%20Society%20for%20Pharmacoeconomics%20and%20Outcomes%20Research%26lt%3B%5C%2Fi%26gt%3B%2024%2C%20no.%202%20%28February%202021%29%3A%20303%5Cu201312.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jval.2020.09.016.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cost-Effectiveness%20of%20Targeted%20Genetic%20Testing%20for%20Breast%20and%20Ovarian%20Cancer%3A%20A%20Systematic%20Review%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Koldehoff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniele%22%2C%22lastName%22%3A%22Civello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Rhiem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22M%5Cu00fcller%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Targeted%20genetic%20testing%20is%20a%20tool%20to%20identify%20women%20at%20increased%20risk%20of%20gynaecological%20cancer.%5CnOBJECTIVE%3A%20This%20systematic%20review%20evaluates%20the%20results%20and%20quality%20of%20cost-effectiveness%20modeling%20studies%20that%20assessed%20targeted%20genetic-based%20screen-and-treat%20strategies%20to%20prevent%20breast%20and%20ovarian%20cancer.%5CnMETHODS%3A%20Using%20MEDLINE%20and%20databases%20of%20the%20Centre%20for%20Reviews%20and%20Dissemination%2C%20we%20searched%20for%20health%20economic%20modeling%20evaluations%20of%20targeted%20genetic-based%20screen-and-treat%20strategies%20to%20prevent%20inheritable%20breast%20and%20ovarian%20cancer%20%28until%20August%202020%29.%20The%20incremental%20cost-effectiveness%20ratios%20%28ICERs%29%20were%20compared.%20Methodological%20variations%20were%20addressed%20by%20evaluating%20the%20model%20conceptualizations%2C%20the%20modeling%20techniques%2C%20parameter%20estimation%20and%20uncertainty%2C%20and%20transparency%20and%20validation%20of%20the%20models.%20Additionally%2C%20the%20reporting%20quality%20of%20each%20study%20was%20assessed.%5CnRESULTS%3A%20Eighteen%20studies%20met%20our%20inclusion%20criteria.%20From%20a%20payer%20perspective%2C%20the%20ICERs%20of%20%281%29%20BRCA%20screening%20for%20high-risk%20women%20without%20cancer%20ranged%20from%20dominating%20the%20no%20test%20strategy%20to%20an%20ICER%20of%20%2421%20700%5C%2Fquality-adjusted%20life%20years%20%28QALY%29.%20In%20studies%20that%20evaluated%20%282%29%20BRCA%20cascade%20screening%20%28ie%2C%20screening%20of%20women%20with%20cancer%20plus%20their%20unaffected%20relatives%29%20compared%20with%20no%20test%2C%20the%20ICERs%20were%20between%20%246500%5C%2FQALY%20and%20%2450%20200%5C%2FQALY.%20Compared%20with%20BRCA%20alone%2C%20%283%29%20multigene%20testing%20in%20women%20without%20cancer%20had%20an%20ICER%20of%20%2451%20800%5C%2FQALY%20%28one%20study%29%2C%20while%20for%20%284%29%20multigene-cascade%20screening%20the%20ICERs%20were%20%2415%20600%5C%2FQALY%2C%20%2456.500%5C%2FQALY%2C%20and%20%2469%20600%5C%2FQALY%20for%20women%20in%20the%20United%20Kingdom%2C%20Norway%2C%20and%20the%20United%20States%2C%20respectively%20%282%20studies%29.%20More%20recently%20published%20studies%20showed%20a%20higher%20methodological%20and%20reporting%20quality.%5CnCONCLUSIONS%3A%20Targeted%20BRCA%20or%20multiple%20gene%20screening%20is%20likely%20to%20be%20cost-effective.%20Methodological%20variations%20could%20be%20decreased%20by%20the%20development%20of%20a%20reference%20model%2C%20which%20may%20serve%20as%20a%20tool%20for%20validation%20of%20present%20and%20future%20cost-effectiveness%20models.%22%2C%22date%22%3A%222021-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jval.2020.09.016%22%2C%22ISSN%22%3A%221524-4733%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubmed.ncbi.nlm.nih.gov%5C%2F33518037%5C%2F%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%22X7PUUBWP%22%2C%22YZ2ZWNUA%22%2C%227ZDA33V6%22%2C%22SG8SD8IJ%22%2C%22W637CI9M%22%2C%22SXDM3NIR%22%2C%22H4RZ68DD%22%2C%22ACPQBWRE%22%5D%2C%22dateModified%22%3A%222024-06-06T10%3A34%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22MLMQ3F4X%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Danner%20et%20al.%22%2C%22parsedDate%22%3A%222020-10-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDanner%2C%20Marion%2C%20Friedemann%20Geiger%2C%20Kai%20Wehkamp%2C%20Jens%20Ulrich%20Rueffer%2C%20Christine%20Kuch%2C%20Leonie%20Sundmacher%2C%20Tove%20Skjelbakken%2C%20et%20al.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fbmjopen.bmj.com%5C%2Fcontent%5C%2F10%5C%2F10%5C%2Fe037575%26%23039%3B%26gt%3BMaking%20shared%20decision-making%20%28SDM%29%20a%20reality%3A%20protocol%20of%20a%20large-scale%20long-term%20SDM%20implementation%20programme%20at%20a%20Northern%20German%20University%20Hospital%26lt%3B%5C%2Fa%26gt%3B.%26quot%3B%20%26lt%3Bi%26gt%3BBMJ%20Open%26lt%3B%5C%2Fi%26gt%3B%2010%2C%20no.%2010%20%28October%201%2C%202020%29%3A%20e037575.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2020-037575.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Making%20shared%20decision-making%20%28SDM%29%20a%20reality%3A%20protocol%20of%20a%20large-scale%20long-term%20SDM%20implementation%20programme%20at%20a%20Northern%20German%20University%20Hospital%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friedemann%22%2C%22lastName%22%3A%22Geiger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22Wehkamp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%20Ulrich%22%2C%22lastName%22%3A%22Rueffer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Kuch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leonie%22%2C%22lastName%22%3A%22Sundmacher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tove%22%2C%22lastName%22%3A%22Skjelbakken%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Rummer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Novelli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Debrouwere%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fueloep%22%2C%22lastName%22%3A%22Scheibler%22%7D%5D%2C%22abstractNote%22%3A%22Introduction%20Shared%20decision-making%20%28SDM%29%20is%20not%20yet%20widely%20used%20when%20making%20decisions%20in%20German%20hospitals.%20Making%20SDM%20a%20reality%20is%20a%20complex%20task.%20It%20involves%20training%20healthcare%20professionals%20in%20SDM%20communication%20and%20enabling%20patients%20to%20actively%20participate%20in%20communication%2C%20in%20addition%20to%20providing%20sound%2C%20easy%20to%20understand%20information%20on%20treatment%20alternatives%20in%20the%20form%20of%20evidence-based%20patient%20decision%20aids%20%28EbPDAs%29.%20This%20project%20funded%20by%20the%20German%20Innovation%20Fund%20aims%20at%20designing%2C%20implementing%20and%20evaluating%20a%20multicomponent%2C%20large-scale%20and%20integrative%20SDM%20programme%5Cu2014called%20SHARE%20TO%20CARE%20%28S2C%29%5Cu2014at%20all%20clinical%20departments%20of%20a%20University%20Hospital%20Campus%20in%20Northern%20Germany%20within%20a%204-year%20time%20period.%5CnMethods%20and%20analysis%20S2C%20tackles%20the%20aforementioned%20components%20of%20SDM%3A%20%281%29%20training%20physicians%20in%20SDM%20communication%2C%20%282%29%20activating%20and%20empowering%20patients%2C%20%283%29%20developing%20EbPDAs%20in%20the%20most%20common%5C%2Frelevant%20diseases%20and%20%284%29%20training%20other%20healthcare%20professionals%20in%20SDM%20coaching.%20S2C%20is%20designed%20together%20with%20patients%20and%20providers.%20The%20physicians%5Cu2019%20training%20programme%20entails%20an%20online%20and%20an%20in%20situ%20training%20module.%20The%20decision%20coach%20training%20is%20based%20on%20a%20similar%20but%20less%20comprehensive%20approach.%20The%20development%20of%20online%20EbPDAs%20follows%20the%20International%20Patient%20Decision%20Aid%20Standards%20and%20includes%20written%2C%20graphical%20and%20video-based%20information.%20Validated%20outcomes%20of%20SDM%20implementation%20are%20measured%20in%20a%20preintervention%20and%20postintervention%20evaluation%20design.%20Process%20evaluation%20accompanies%20programme%20implementation.%20Health%20economic%20impact%20of%20the%20intervention%20is%20investigated%20using%20a%20propensity-score-matched%20approach%20based%20on%20potentially%20preference-sensitive%20hospital%20decisions.%5CnEthics%20and%20dissemination%20Ethics%20committee%20review%20approval%20has%20been%20obtained%20from%20Medical%20Ethics%20Committee%20of%20the%20Medical%20Faculty%20of%20the%20Christian-Albrechts-University%20Kiel.%20Project%20information%20and%20results%20will%20be%20disseminated%20at%20conferences%2C%20on%20project-hosted%20websites%20at%20University%20Hospital%20Medical%20Center%20Schleswig%20Holstein%20and%20by%20S2C%20as%20well%20as%20in%20peer-reviewed%20and%20professional%20journals.%22%2C%22date%22%3A%222020%5C%2F10%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1136%5C%2Fbmjopen-2020-037575%22%2C%22ISSN%22%3A%222044-6055%2C%202044-6055%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fbmjopen.bmj.com%5C%2Fcontent%5C%2F10%5C%2F10%5C%2Fe037575%22%2C%22collections%22%3A%5B%22ZAW5JYVL%22%2C%22ZFT52UPQ%22%2C%2246NNKHWR%22%2C%223L4EXKAR%22%2C%22J987ELTY%22%2C%22SPWXRLZV%22%2C%227C3HQD4E%22%2C%22ZKMQLZWF%22%2C%22DCC2W2YR%22%2C%227ZDA33V6%22%2C%22P9CVNWVH%22%2C%22ERQ322N6%22%5D%2C%22dateModified%22%3A%222024-05-17T08%3A59%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22UBE43GCN%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22M%5Cu00fcller%20et%20al.%22%2C%22parsedDate%22%3A%222019-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BM%5Cu00fcller%2C%20Dirk%2C%20Marion%20Danner%2C%20Rita%20Schmutzler%2C%20Christoph%20Engel%2C%20Kirsten%20Wassermann%2C%20Bj%5Cu00f6rn%20Stollenwerk%2C%20Stephanie%20Stock%2C%20and%20Kerstin%20Rhiem.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fpubmed.ncbi.nlm.nih.gov%5C%2F30790097%5C%2F%26%23039%3B%26gt%3BEconomic%20modeling%20of%20risk-adapted%20screen-and-treat%20strategies%20in%20women%20at%20high%20risk%20for%20breast%20or%20ovarian%20cancer%26lt%3B%5C%2Fa%26gt%3B.%26quot%3B%20%26lt%3Bi%26gt%3BThe%20European%20Journal%20of%20Health%20Economics%3A%20HEPAC%3A%20Health%20Economics%20in%20Prevention%20and%20Care%26lt%3B%5C%2Fi%26gt%3B%2020%2C%20no.%205%20%28July%202019%29%3A%20739%5Cu201350.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10198-019-01038-1.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Economic%20modeling%20of%20risk-adapted%20screen-and-treat%20strategies%20in%20women%20at%20high%20risk%20for%20breast%20or%20ovarian%20cancer%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22M%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rita%22%2C%22lastName%22%3A%22Schmutzler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kirsten%22%2C%22lastName%22%3A%22Wassermann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bj%5Cu00f6rn%22%2C%22lastName%22%3A%22Stollenwerk%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Rhiem%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20The%20%26%23039%3BGerman%20Consortium%20for%20Hereditary%20Breast%20and%20Ovarian%20Cancer%26%23039%3B%20%28GC-HBOC%29%20offers%20women%20with%20a%20family%20history%20of%20breast%20and%20ovarian%20cancer%20genetic%20counseling.%20The%20aim%20of%20this%20modeling%20study%20was%20to%20evaluate%20the%20cost-effectiveness%20of%20genetic%20testing%20for%20BRCA%201%5C%2F2%20in%20women%20with%20a%20high%20familial%20risk%20followed%20by%20different%20preventive%20interventions%20%28intensified%20surveillance%2C%20risk-reducing%20bilateral%20mastectomy%2C%20risk-reducing%20bilateral%20salpingo-oophorectomy%2C%20or%20both%20mastectomy%20and%20salpingo-oophorectomy%29%20compared%20to%20no%20genetic%20test.%5CnMETHODS%3A%20A%20Markov%20model%20with%20a%20lifelong%20time%20horizon%20was%20developed%20for%20a%20cohort%20of%2035-year-old%20women%20with%20a%20BRCA%201%5C%2F2%20mutation%20probability%20of%20%5Cu2265%5Cu200910%25.%20The%20perspective%20of%20the%20German%20statutory%20health%20insurance%20%28SHI%29%20was%20adopted.%20The%20model%20included%20the%20health%20states%20%26%23039%3Bwell%26%23039%3B%20%28women%20with%20increased%20risk%29%2C%20%26%23039%3Bbreast%20cancer%20without%20metastases%26%23039%3B%2C%20%26%23039%3Bbreast%20cancer%20with%20metastases%26%23039%3B%2C%20%26%23039%3Bovarian%20cancer%26%23039%3B%2C%20%26%23039%3Bdeath%26%23039%3B%2C%20and%20two%20post%20%28non-metastatic%29%20breast%20or%20ovarian%20cancer%20states.%20Outcomes%20were%20costs%2C%20quality%20of%20life%20years%20gained%20%28QALYs%29%20and%20life%20years%20gained%20%28LYG%29.%20Important%20data%20used%20for%20the%20model%20were%20obtained%20from%204380%20women%20enrolled%20in%20the%20GC-HBOC.%5CnRESULTS%3A%20Compared%20with%20the%20no%20test%20strategy%2C%20genetic%20testing%20with%20subsequent%20surgical%20and%20non-surgical%20treatment%20options%20provided%20to%20women%20with%20deleterious%20BRCA%201%20or%202%20mutations%20resulted%20in%20additional%20costs%20of%20%5Cu20ac7256%20and%20additional%20QALYs%20of%200%2C43%20%28incremental%20cost-effectiveness%20ratio%20of%20%5Cu20ac17%2C027%20per%20QALY%3B%20cost%20per%20LYG%3A%20%5Cu20ac22%2C318%29.%20The%20results%20were%20robust%20in%20deterministic%20and%20probabilistic%20sensitivity%20analyses.%5CnCONCLUSION%3A%20The%20provision%20of%20genetic%20testing%20to%20high-risk%20women%20with%20a%20BRCA1%20and%20two%20mutation%20probability%20of%20%5Cu2265%5Cu200910%25%20based%20on%20the%20individual%20family%20cancer%20history%20appears%20to%20be%20a%20cost-effective%20option%20for%20the%20SHI.%22%2C%22date%22%3A%222019-07%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10198-019-01038-1%22%2C%22ISSN%22%3A%221618-7601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubmed.ncbi.nlm.nih.gov%5C%2F30790097%5C%2F%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%227ZDA33V6%22%2C%22SG8SD8IJ%22%2C%22W637CI9M%22%2C%22P9CVNWVH%22%2C%22N24UXA6K%22%2C%22SXDM3NIR%22%2C%226CWITS3E%22%2C%22H4RZ68DD%22%5D%2C%22dateModified%22%3A%222024-06-05T08%3A58%3A17Z%22%7D%7D%2C%7B%22key%22%3A%224MKPVQCV%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22M%5Cu00fcller%20et%20al.%22%2C%22parsedDate%22%3A%222018-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BM%26%23xFC%3Bller%2C%20Dirk%2C%20Marion%20Danner%2C%20Kerstin%20Rhiem%2C%20Bj%26%23xF6%3Brn%20Stollenwerk%2C%20Christoph%20Engel%2C%20Linda%20Rasche%2C%20Lisa%20Borsi%2C%20Rita%20Schmutzler%2C%20and%20Stephanie%20Stock.%20%26%23x201C%3BCost-Effectiveness%20of%20Different%20Strategies%20to%20Prevent%20Breast%20and%20Ovarian%20Cancer%20in%20German%20Women%20with%20a%20BRCA%201%20or%202%20Mutation.%26%23x201D%3B%20%26lt%3Bi%26gt%3BThe%20European%20Journal%20of%20Health%20Economics%3A%20HEPAC%3A%20Health%20Economics%20in%20Prevention%20and%20Care%26lt%3B%5C%2Fi%26gt%3B%2019%2C%20no.%203%20%28April%202018%29%3A%20341%26%23x2013%3B53.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10198-017-0887-5%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10198-017-0887-5%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cost-effectiveness%20of%20different%20strategies%20to%20prevent%20breast%20and%20ovarian%20cancer%20in%20German%20women%20with%20a%20BRCA%201%20or%202%20mutation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22M%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Rhiem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bj%5Cu00f6rn%22%2C%22lastName%22%3A%22Stollenwerk%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Linda%22%2C%22lastName%22%3A%22Rasche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lisa%22%2C%22lastName%22%3A%22Borsi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rita%22%2C%22lastName%22%3A%22Schmutzler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Women%20with%20a%20BRCA1%20or%20BRCA2%20mutation%20are%20at%20increased%20risk%20of%20developing%20breast%20and%5C%2For%20ovarian%20cancer.%20This%20economic%20modeling%20study%20evaluated%20different%20preventive%20interventions%20for%2030-year-old%20women%20with%20a%20confirmed%20BRCA%20%281%20or%202%29%20mutation.%5CnMETHODS%3A%20A%20Markov%20model%20was%20developed%20to%20estimate%20the%20costs%20and%20benefits%20%5Bi.e.%2C%20quality-adjusted%20life%20years%20%28QALYs%29%2C%20and%20life%20years%20gained%20%28LYG%29%5D%20associated%20with%20prophylactic%20bilateral%20mastectomy%20%28BM%29%2C%20prophylactic%20bilateral%20salpingo-oophorectomy%20%28BSO%29%2C%20BM%20plus%20BSO%2C%20BM%20plus%20BSO%20at%20age%2040%2C%20and%20intensified%20surveillance.%20Relevant%20input%20data%20was%20obtained%20from%20a%20large%20German%20database%20including%205902%20women%20with%20BRCA%201%20or%202%2C%20and%20from%20the%20literature.%20The%20analysis%20was%20performed%20from%20the%20German%20Statutory%20Health%20Insurance%20%28SHI%29%20perspective.%20In%20order%20to%20assess%20the%20robustness%20of%20the%20results%2C%20deterministic%20and%20probabilistic%20sensitivity%20analyses%20were%20performed.%5CnRESULTS%3A%20With%20costs%20of%20%5Cu20ac29%2C434%20and%20a%20gain%20in%20QALYs%20of%2017.7%20%28LYG%2019.9%29%2C%20BM%20plus%20BSO%20at%20age%2030%20was%20less%20expensive%20and%20more%20effective%20than%20the%20other%20strategies%2C%20followed%20by%20BM%20plus%20BSO%20at%20age%2040.%20Women%20who%20were%20offered%20the%20surveillance%20strategy%20had%20the%20highest%20costs%20at%20the%20lowest%20gain%20in%20QALYs%5C%2FLYS.%20In%20the%20probabilistic%20sensitivity%20analysis%2C%20the%20probability%20of%20cost-saving%20was%2057%25%20for%20BM%20plus%20BSO.%20At%20a%20WTP%20of%2010%2C000%20%5Cu20ac%20per%20QALY%2C%20the%20probability%20of%20the%20intervention%20being%20cost-effective%20was%2080%25.%5CnCONCLUSIONS%3A%20From%20the%20SHI%20perspective%2C%20undergoing%20BM%20plus%20immediate%20BSO%20should%20be%20recommended%20to%20BRCA%201%20or%202%20mutation%20carriers%20due%20to%20its%20favorable%20comparative%20cost-effectiveness.%22%2C%22date%22%3A%222018-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10198-017-0887-5%22%2C%22ISSN%22%3A%221618-7601%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%227ZDA33V6%22%2C%22SG8SD8IJ%22%2C%22W637CI9M%22%2C%226CWITS3E%22%2C%22H4RZ68DD%22%5D%2C%22dateModified%22%3A%222024-05-15T13%3A45%3A09Z%22%7D%7D%2C%7B%22key%22%3A%22EZET2YIZ%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vennedey%20et%20al.%22%2C%22parsedDate%22%3A%222018%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BVennedey%2C%20Vera%2C%20Sonja%20Hm%20Derman%2C%20Micka%26%23xEB%3Bl%20Hiligsmann%2C%20Daniele%20Civello%2C%20Anja%20Schwalm%2C%20Astrid%20Seidl%2C%20F%26%23xFC%3Bl%26%23xF6%3Bp%20Scheibler%2C%20Stephanie%20Stock%2C%20Michael%20J.%20Noack%2C%20and%20Marion%20Danner.%20%26%23x201C%3BPatients%26%23x2019%3B%20Preferences%20in%20Periodontal%20Disease%20Treatment%20Elicited%20alongside%20an%20IQWiG%20Benefit%20Assessment%3A%20A%20Feasibility%20Study.%26%23x201D%3B%20%26lt%3Bi%26gt%3BPatient%20Preference%20and%20Adherence%26lt%3B%5C%2Fi%26gt%3B%2012%20%282018%29%3A%202437%26%23x2013%3B47.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.2147%5C%2FPPA.S176067%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.2147%5C%2FPPA.S176067%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Patients%27%20preferences%20in%20periodontal%20disease%20treatment%20elicited%20alongside%20an%20IQWiG%20benefit%20assessment%3A%20a%20feasibility%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vera%22%2C%22lastName%22%3A%22Vennedey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sonja%20Hm%22%2C%22lastName%22%3A%22Derman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Hiligsmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniele%22%2C%22lastName%22%3A%22Civello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Schwalm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Astrid%22%2C%22lastName%22%3A%22Seidl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F%5Cu00fcl%5Cu00f6p%22%2C%22lastName%22%3A%22Scheibler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%20J.%22%2C%22lastName%22%3A%22Noack%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%5D%2C%22abstractNote%22%3A%22Background%20and%20purpose%3A%20The%20German%20Institute%20for%20Quality%20and%20Efficiency%20in%20Health%20Care%20%28IQWiG%29%20previously%20tested%20two%20preference%20elicitation%20methods%20in%20pilot%20projects%20and%20regarded%20them%20as%20generally%20feasible%20for%20prioritizing%20outcome-specific%20results%20of%20benefit%20assessment.%20The%20present%20study%20aimed%20to%20investigate%20the%20feasibility%20of%20completing%20a%20discrete%20choice%20experiment%20%28DCE%29%20within%203%20months%20and%20to%20determine%20the%20relative%20importance%20of%20attributes%20of%20periodontal%20disease%20and%20its%20treatment.%5CnPatients%20and%20methods%3A%20This%20preference%20elicitation%20was%20conducted%20alongside%20the%20IQWiG%20benefit%20assessment%20of%20systematic%20treatments%20of%20periodontal%20diseases.%20Attributes%20were%20defined%20based%20on%20the%20benefit%20assessment%2C%20literature%20review%2C%20and%20patients%26%23039%3B%20and%20periodontologists%26%23039%3B%20interviews.%20The%20DCE%20survey%20was%20completed%20by%20patients%20with%20a%20history%20of%20periodontal%20disease.%20Preferences%20were%20elicited%20for%20the%20attributes%20%26quot%3Btooth%20loss%20within%20next%2010%20years%26quot%3B%2C%20%26quot%3Bown%20costs%20for%20treatment%2C%20follow-up%20visits%2C%20re-treatment%26quot%3B%2C%20%26quot%3Bcomplaints%20and%20symptoms%26quot%3B%2C%20and%20%26quot%3Bfrequency%20of%20follow-up%20visits%26quot%3B.%20Patients%20completed%20a%20self-administered%20questionnaire%20including%2012%20choice%20tasks.%20Data%20were%20analyzed%20using%20a%20random%20parameters%20logit%20model.%20The%20relative%20attribute%20importance%20was%20calculated%20based%20on%20level%20ranges.%5CnResults%3A%20Within%203%20months%2C%20survey%20development%2C%20data%20collection%20among%20267%20patients%2C%20data%20analysis%2C%20and%20provision%20of%20a%20study%20report%20could%20be%20completed.%20The%20analysis%20showed%20that%20tooth%20loss%20%28score%200.73%29%20was%20the%20most%20important%20attribute%20in%20patients%26%23039%3B%20decisions%2C%20followed%20by%20complaints%20and%20symptoms%20%280.22%29%2C%20frequency%20of%20follow-up%20visits%20%280.02%29%2C%20and%20costs%20%280.03%29%20%28relative%20importance%20scores%20summing%20up%20to%201%29.%5CnConclusion%3A%20A%20preference%20analysis%20performing%20a%20DCE%20can%20be%20generally%20feasible%20within%203%20months%3B%20however%2C%20a%20good%20research%20infrastructure%20and%20access%20to%20patients%20is%20required.%20Outcomes%20used%20in%20benefit%20assessments%20might%20need%20to%20be%20adapted%20to%20be%20used%20in%20preference%20analyses.%22%2C%22date%22%3A%222018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.2147%5C%2FPPA.S176067%22%2C%22ISSN%22%3A%221177-889X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%223L4EXKAR%22%2C%22X7PUUBWP%22%2C%22YZ2ZWNUA%22%2C%227ZDA33V6%22%2C%22WK7W2JLX%22%5D%2C%22dateModified%22%3A%222024-05-26T15%3A47%3A09Z%22%7D%7D%2C%7B%22key%22%3A%22KDBWM62P%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bien%20et%20al.%22%2C%22parsedDate%22%3A%222017-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BBien%2C%20Daniela%20R.%2C%20Marion%20Danner%2C%20Vera%20Vennedey%2C%20Daniele%20Civello%2C%20Silvia%20M.%20Evers%2C%20and%20Micka%26%23xEB%3Bl%20Hiligsmann.%20%26%23x201C%3BPatients%26%23x2019%3B%20Preferences%20for%20Outcome%2C%20Process%20and%20Cost%20Attributes%20in%20Cancer%20Treatment%3A%20A%20Systematic%20Review%20of%20Discrete%20Choice%20Experiments.%26%23x201D%3B%20%26lt%3Bi%26gt%3BThe%20Patient%26lt%3B%5C%2Fi%26gt%3B%2010%2C%20no.%205%20%28October%202017%29%3A%20553%26%23x2013%3B65.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40271-017-0235-y%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40271-017-0235-y%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Patients%27%20Preferences%20for%20Outcome%2C%20Process%20and%20Cost%20Attributes%20in%20Cancer%20Treatment%3A%20A%20Systematic%20Review%20of%20Discrete%20Choice%20Experiments%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniela%20R.%22%2C%22lastName%22%3A%22Bien%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vera%22%2C%22lastName%22%3A%22Vennedey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniele%22%2C%22lastName%22%3A%22Civello%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silvia%20M.%22%2C%22lastName%22%3A%22Evers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Hiligsmann%22%7D%5D%2C%22abstractNote%22%3A%22INTRODUCTION%3A%20As%20several%20studies%20have%20been%20conducted%20to%20elicit%20patients%26%23039%3B%20preferences%20for%20cancer%20treatment%2C%20it%20is%20important%20to%20provide%20an%20overview%20and%20synthesis%20of%20these%20studies.%20This%20study%20aimed%20to%20systematically%20review%20discrete%20choice%20experiments%20%28DCEs%29%20about%20patients%26%23039%3B%20preferences%20for%20cancer%20treatment%20and%20assessed%20the%20relative%20importance%20of%20outcome%2C%20process%20and%20cost%20attributes.%5CnMETHODS%3A%20A%20systematic%20literature%20review%20was%20conducted%20using%20PubMed%20and%20EMBASE%20to%20identify%20all%20DCEs%20investigating%20patients%26%23039%3B%20preferences%20for%20cancer%20treatment%20between%20January%202010%20and%20April%202016.%20Data%20were%20extracted%20using%20a%20predefined%20extraction%20sheet%2C%20and%20a%20reporting%20quality%20assessment%20was%20applied%20to%20all%20studies.%20Attributes%20were%20classified%20into%20outcome%2C%20process%20and%20cost%20attributes%2C%20and%20their%20relative%20importance%20was%20assessed.%5CnRESULTS%3A%20A%20total%20of%2028%20DCEs%20were%20identified.%20More%20than%20half%20of%20the%20studies%20%2856%25%29%20received%20an%20aggregate%20score%20lower%20than%204%20on%20the%20PREFS%20%28Purpose%2C%20Respondents%2C%20Explanation%2C%20Findings%2C%20Significance%29%205-point%20scale.%20Most%20attributes%20were%20related%20to%20outcome%20%2870%25%29%2C%20followed%20by%20process%20%2825%25%29%20and%20cost%20%285%25%29.%20Outcome%20attributes%20were%20most%20often%20significant%20%2881%25%29%2C%20followed%20by%20process%20%2873%25%29%20and%20cost%20%2867%25%29.%20The%20relative%20importance%20of%20outcome%20attributes%20was%20ranked%20highest%20in%2082%25%20of%20the%20cases%20where%20it%20was%20included%2C%20followed%20by%20cost%20%2843%25%29%20and%20process%20%2812%25%29.%5CnCONCLUSION%3A%20This%20systematic%20review%20suggests%20that%20attributes%20related%20to%20cancer%20treatment%20outcomes%20are%20the%20most%20important%20for%20patients.%20Process%20and%20cost%20attributes%20were%20less%20often%20included%20in%20studies%20but%20were%20still%20%28but%20less%29%20important%20to%20patients%20in%20most%20studies.%20Clinicians%20and%20decision%20makers%20should%20be%20aware%20that%20attribute%20importance%20might%20be%20influenced%20by%20level%20selection%20for%20that%20attribute.%22%2C%22date%22%3A%222017-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs40271-017-0235-y%22%2C%22ISSN%22%3A%221178-1661%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22X7PUUBWP%22%2C%22YZ2ZWNUA%22%2C%227ZDA33V6%22%2C%22W637CI9M%22%2C%22N24UXA6K%22%2C%22ACPQBWRE%22%5D%2C%22dateModified%22%3A%222024-06-06T11%3A07%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22NP9TZ5G6%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Danner%20et%20al.%22%2C%22parsedDate%22%3A%222017-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDanner%2C%20Marion%2C%20Vera%20Vennedey%2C%20Micka%26%23xEB%3Bl%20Hiligsmann%2C%20Sascha%20Fauser%2C%20Christian%20Gross%2C%20and%20Stephanie%20Stock.%20%26%23x201C%3BComparing%20Analytic%20Hierarchy%20Process%20and%20Discrete-Choice%20Experiment%20to%20Elicit%20Patient%20Preferences%20for%20Treatment%20Characteristics%20in%20Age-Related%20Macular%20Degeneration.%26%23x201D%3B%20%26lt%3Bi%26gt%3BValue%20in%20Health%3A%20The%20Journal%20of%20the%20International%20Society%20for%20Pharmacoeconomics%20and%20Outcomes%20Research%26lt%3B%5C%2Fi%26gt%3B%2020%2C%20no.%208%20%28September%202017%29%3A%201166%26%23x2013%3B73.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jval.2017.04.022%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jval.2017.04.022%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Comparing%20Analytic%20Hierarchy%20Process%20and%20Discrete-Choice%20Experiment%20to%20Elicit%20Patient%20Preferences%20for%20Treatment%20Characteristics%20in%20Age-Related%20Macular%20Degeneration%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vera%22%2C%22lastName%22%3A%22Vennedey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Hiligsmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sascha%22%2C%22lastName%22%3A%22Fauser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Gross%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20In%20this%20study%2C%20we%20conducted%20an%20analytic%20hierarchy%20process%20%28AHP%29%20and%20a%20discrete%20choice%20experiment%20%28DCE%29%20to%20elicit%20the%20preferences%20of%20patients%20with%20age-related%20macular%20degeneration%20using%20identical%20attributes%20and%20levels.%5CnOBJECTIVES%3A%20To%20compare%20preference-based%20weights%20for%20age-related%20macular%20degeneration%20treatment%20attributes%20and%20levels%20generated%20by%20two%20elicitation%20methods.%20The%20properties%20of%20both%20methods%20were%20assessed%2C%20including%20ease%20of%20instrument%20use.%5CnMETHODS%3A%20A%20DCE%20and%20an%20AHP%20experiment%20were%20designed%20on%20the%20basis%20of%20five%20attributes.%20Preference-based%20weights%20were%20generated%20using%20the%20matrix%20multiplication%20method%20for%20attributes%20and%20levels%20in%20AHP%20and%20a%20mixed%20multinomial%20logit%20model%20for%20levels%20in%20the%20DCE.%20Attribute%20importance%20was%20further%20compared%20using%20coefficient%20%28DCE%29%20and%20weight%20%28AHP%29%20level%20ranges.%20The%20questionnaire%20difficulty%20was%20rated%20on%20a%20qualitative%20scale.%20Patients%20were%20asked%20to%20think%20aloud%20while%20providing%20their%20judgments.%5CnRESULTS%3A%20AHP%20and%20DCE%20generated%20similar%20results%20regarding%20levels%2C%20stressing%20a%20preference%20for%20visual%20improvement%2C%20frequent%20monitoring%2C%20on-demand%20and%20less%20frequent%20injection%20schemes%2C%20approved%20drugs%2C%20and%20mild%20side%20effects.%20Attribute%20weights%20derived%20on%20the%20basis%20of%20level%20ranges%20led%20to%20a%20ranking%20that%20was%20opposite%20to%20the%20AHP%20directly%20calculated%20attribute%20weights.%20For%20example%2C%20visual%20function%20ranked%20first%20in%20the%20AHP%20and%20last%20on%20the%20basis%20of%20level%20ranges.%5CnCONCLUSIONS%3A%20The%20results%20across%20the%20methods%20were%20similar%2C%20with%20one%20exception%3A%20the%20directly%20measured%20AHP%20attribute%20weights%20were%20different%20from%20the%20level-based%20interpretation%20of%20attribute%20importance%20in%20both%20DCE%20and%20AHP.%20The%20dependence%5C%2Findependence%20of%20attribute%20importance%20on%20level%20ranges%20in%20DCE%20and%20AHP%2C%20respectively%2C%20should%20be%20taken%20into%20account%20when%20choosing%20a%20method%20to%20support%20decision%20making.%22%2C%22date%22%3A%222017-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jval.2017.04.022%22%2C%22ISSN%22%3A%221524-4733%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%22X7PUUBWP%22%2C%227ZDA33V6%22%5D%2C%22dateModified%22%3A%222024-03-11T12%3A29%3A07Z%22%7D%7D%2C%7B%22key%22%3A%22MJ4TL7X3%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Danner%20et%20al.%22%2C%22parsedDate%22%3A%222016-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDanner%2C%20Marion%2C%20Vera%20Vennedey%2C%20Micka%26%23xEB%3Bl%20Hiligsmann%2C%20Sascha%20Fauser%2C%20and%20Stephanie%20Stock.%20%26%23x201C%3BFocus%20Groups%20in%20Elderly%20Ophthalmologic%20Patients%3A%20Setting%20the%20Stage%20for%20Quantitative%20Preference%20Elicitation.%26%23x201D%3B%20%26lt%3Bi%26gt%3BThe%20Patient%26lt%3B%5C%2Fi%26gt%3B%209%2C%20no.%201%20%28February%202016%29%3A%2047%26%23x2013%3B57.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40271-015-0122-3%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40271-015-0122-3%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Focus%20Groups%20in%20Elderly%20Ophthalmologic%20Patients%3A%20Setting%20the%20Stage%20for%20Quantitative%20Preference%20Elicitation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vera%22%2C%22lastName%22%3A%22Vennedey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Hiligsmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sascha%22%2C%22lastName%22%3A%22Fauser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20Patients%20suffering%20from%20age-related%20macular%20degeneration%20%28AMD%29%20are%20rarely%20actively%20involved%20in%20decision-making%2C%20despite%20facing%20preference-sensitive%20treatment%20decisions.%20This%20paper%20presents%20a%20qualitative%20study%20to%20prepare%20quantitative%20preference%20elicitation%20in%20AMD%20patients.%20The%20aims%20of%20this%20study%20were%20%281%29%20to%20gain%20familiarity%20with%20and%20learn%20about%20the%20special%20requirements%20of%20the%20AMD%20patient%20population%20for%20quantitative%20data%20collection%3B%20and%20%282%29%20to%20select%5C%2Frefine%20patient-relevant%20treatment%20attributes%20and%20levels%2C%20and%20gain%20insights%20into%20preference%20structures.%5CnMETHODS%3A%20Semi-structured%20focus%20group%20interviews%20were%20performed.%20An%20interview%20guide%20including%20preselected%20categories%20in%20the%20form%20of%20seven%20potentially%20patient-relevant%20treatment%20attributes%20was%20followed.%20To%20identify%20the%20most%20patient-relevant%20treatment%20attributes%2C%20a%20ranking%20exercise%20was%20performed.%20Deductive%20content%20analyses%20were%20done%20by%20two%20independent%20reviewers%20for%20each%20attribute%20to%20derive%20subcategories%20%28potential%20levels%20of%20attributes%29%20and%20depict%20preference%20trends.%5CnRESULTS%3A%20The%20focus%20group%20interviews%20included%2021%20patients.%20The%20interviews%20revealed%20that%20quantitative%20preference%20surveys%20in%20this%20population%20will%20have%20to%20be%20interviewer%20assisted%20to%20make%20the%20survey%20feasible%20for%20patients.%20The%20five%20most%20patient-relevant%20attributes%20were%20the%20effect%20on%20visual%20function%20%5Branking%20score%20%28RS%29%3A%20139%5D%2C%20injection%20frequency%20%28RS%3A%20101%29%2C%20approval%20status%20%28RS%3A%2083%29%2C%20side%20effects%20%28RS%3A%2079%29%2C%20and%20monitoring%20frequency%20%28RS%3A%2076%29.%20Attribute%20and%20level%20refinement%20was%20based%20on%20patients%26%23039%3B%20statements.%20Preference%20trends%20and%20dependencies%20between%20attributes%20informed%20the%20quantitative%20instrument%20design.%5CnCONCLUSION%3A%20This%20study%20suggests%20that%20qualitative%20research%20is%20a%20very%20helpful%20step%20to%20prepare%20the%20design%20and%20administration%20of%20quantitative%20preference%20elicitation%20instruments.%20It%20especially%20facilitated%20familiarization%20with%20the%20target%20population%20and%20its%20preferences%2C%20and%20it%20supported%20attribute%5C%2Flevel%20refinement.%22%2C%22date%22%3A%222016-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs40271-015-0122-3%22%2C%22ISSN%22%3A%221178-1661%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%22X7PUUBWP%22%2C%227ZDA33V6%22%5D%2C%22dateModified%22%3A%222024-03-11T12%3A25%3A38Z%22%7D%7D%2C%7B%22key%22%3A%222VAVTMM9%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Danner%20et%20al.%22%2C%22parsedDate%22%3A%222016%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BDanner%2C%20Marion%2C%20Vera%20Vennedey%2C%20Micka%5Cu00ebl%20Hiligsmann%2C%20Sascha%20Fauser%2C%20Christian%20Gross%2C%20and%20Stephanie%20Stock.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttp%3A%5C%2F%5C%2Flink.springer.com%5C%2F10.1007%5C%2Fs40271-016-0179-7%26%23039%3B%26gt%3BHow%20Well%20Can%20Analytic%20Hierarchy%20Process%20be%20Used%20to%20Elicit%20Individual%20Preferences%3F%20Insights%20from%20a%20Survey%20in%20Patients%20Suffering%20from%20Age-Related%20Macular%20Degeneration%26lt%3B%5C%2Fa%26gt%3B.%26quot%3B%20%26lt%3Bi%26gt%3BThe%20Patient%20-%20Patient-Centered%20Outcomes%20Research%26lt%3B%5C%2Fi%26gt%3B%209%2C%20no.%205%20%282016%29%3A%20481%5Cu201392.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs40271-016-0179-7.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22How%20Well%20Can%20Analytic%20Hierarchy%20Process%20be%20Used%20to%20Elicit%20Individual%20Preferences%3F%20Insights%20from%20a%20Survey%20in%20Patients%20Suffering%20from%20Age-Related%20Macular%20Degeneration%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vera%22%2C%22lastName%22%3A%22Vennedey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Hiligsmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sascha%22%2C%22lastName%22%3A%22Fauser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Gross%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2210%5C%2F2016%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs40271-016-0179-7%22%2C%22ISSN%22%3A%221178-1653%2C%201178-1661%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Flink.springer.com%5C%2F10.1007%5C%2Fs40271-016-0179-7%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%22X7PUUBWP%22%2C%227ZDA33V6%22%5D%2C%22dateModified%22%3A%222024-03-11T08%3A12%3A21Z%22%7D%7D%2C%7B%22key%22%3A%22QI4GX4H7%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vennedey%20et%20al.%22%2C%22parsedDate%22%3A%222016%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BVennedey%2C%20Vera%2C%20Marion%20Danner%2C%20Silvia%20Maa%20Evers%2C%20Sascha%20Fauser%2C%20Stephanie%20Stock%2C%20Carmen%20D.%20Dirksen%2C%20and%20Micka%26%23xEB%3Bl%20Hiligsmann.%20%26%23x201C%3BUsing%20Qualitative%20Research%20to%20Facilitate%20the%20Interpretation%20of%20Quantitative%20Results%20from%20a%20Discrete%20Choice%20Experiment%3A%20Insights%20from%20a%20Survey%20in%20Elderly%20Ophthalmologic%20Patients.%26%23x201D%3B%20%26lt%3Bi%26gt%3BPatient%20Preference%20and%20Adherence%26lt%3B%5C%2Fi%26gt%3B%2010%20%282016%29%3A%20993%26%23x2013%3B1002.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.2147%5C%2FPPA.S101584%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.2147%5C%2FPPA.S101584%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Using%20qualitative%20research%20to%20facilitate%20the%20interpretation%20of%20quantitative%20results%20from%20a%20discrete%20choice%20experiment%3A%20insights%20from%20a%20survey%20in%20elderly%20ophthalmologic%20patients%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vera%22%2C%22lastName%22%3A%22Vennedey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silvia%20Maa%22%2C%22lastName%22%3A%22Evers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sascha%22%2C%22lastName%22%3A%22Fauser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carmen%20D.%22%2C%22lastName%22%3A%22Dirksen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Micka%5Cu00ebl%22%2C%22lastName%22%3A%22Hiligsmann%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Age-related%20macular%20degeneration%20%28AMD%29%20is%20the%20leading%20cause%20of%20visual%20impairment%20and%20blindness%20in%20industrialized%20countries.%20Currently%2C%20mainly%20three%20treatment%20options%20are%20available%2C%20which%20are%20all%20intravitreal%20injections%2C%20but%20differ%20with%20regard%20to%20the%20frequency%20of%20injections%20needed%2C%20their%20approval%20status%2C%20and%20cost.%20This%20study%20aims%20to%20estimate%20patients%26%23039%3B%20preferences%20for%20characteristics%20of%20treatment%20options%20for%20neovascular%20AMD.%5CnMETHODS%3A%20An%20interviewer-assisted%20discrete%20choice%20experiment%20was%20conducted%20among%20patients%20suffering%20from%20AMD%20treated%20with%20intravitreal%20injections.%20A%20Bayesian%20efficient%20design%20was%20used%20for%20the%20development%20of%2012%20choice%20tasks.%20In%20each%20task%20patients%20indicated%20their%20preference%20for%20one%20out%20of%20two%20treatment%20scenarios%20described%20by%20the%20attributes%3A%20side%20effects%2C%20approval%20status%2C%20effect%20on%20visual%20function%2C%20injection%20and%20monitoring%20frequency.%20While%20answering%20the%20choice%20tasks%2C%20patients%20were%20asked%20to%20think%20aloud%20and%20explain%20the%20reasons%20for%20choosing%20or%20rejecting%20specific%20characteristics.%20Quantitative%20data%20were%20analyzed%20with%20a%20mixed%20multinomial%20logit%20model.%5CnRESULTS%3A%20Eighty-six%20patients%20completed%20the%20questionnaire.%20Patients%20significantly%20preferred%20treatments%20that%20improve%20visual%20function%2C%20are%20approved%2C%20are%20administered%20in%20a%20pro%20re%20nata%20regimen%20%28as%20needed%29%2C%20and%20are%20accompanied%20by%20bimonthly%20monitoring.%20Patients%20significantly%20disliked%20less%20frequent%20monitoring%20visits%20%28every%204%20months%29%20and%20explained%20this%20was%20due%20to%20fear%20of%20deterioration%20being%20left%20unnoticed%2C%20and%20in%20turn%20experiencing%20disease%20deterioration.%20Significant%20preference%20heterogeneity%20was%20found%20for%20all%20levels%20except%20for%20bimonthly%20monitoring%20visits%20and%20severe%2C%20rare%20eye-related%20side%20effects.%20Patients%20gave%20clear%20explanations%20of%20their%20individual%20preferences%20during%20the%20interviews.%5CnCONCLUSION%3A%20Significant%20preference%20trends%20were%20discernible%20for%20the%20overall%20sample%2C%20despite%20the%20preference%20heterogeneity%20for%20most%20treatment%20characteristics.%20Patients%20like%20to%20be%20monitored%20and%20treated%20regularly%2C%20but%20not%20too%20frequently%20or%20infrequently.%20The%20results%20of%20our%20qualitative%20research%20facilitated%20the%20interpretation%20of%20the%20quantitative%20data%20collected%20in%20this%20study.%22%2C%22date%22%3A%222016%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.2147%5C%2FPPA.S101584%22%2C%22ISSN%22%3A%221177-889X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%22X7PUUBWP%22%2C%227ZDA33V6%22%5D%2C%22dateModified%22%3A%222024-03-11T12%3A18%3A03Z%22%7D%7D%2C%7B%22key%22%3A%229AUDE2ZF%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pendzialek%20et%20al.%22%2C%22parsedDate%22%3A%222015-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BPendzialek%2C%20Jonas%20B.%2C%20Marion%20Danner%2C%20Dusan%20Simic%2C%20and%20Stephanie%20Stock.%20%26%23x201C%3BPrice%20Elasticities%20in%20the%20German%20Statutory%20Health%20Insurance%20Market%20before%20and%20after%20the%20Health%20Care%20Reform%20of%202009.%26%23x201D%3B%20%26lt%3Bi%26gt%3BHealth%20Policy%20%28Amsterdam%2C%20Netherlands%29%26lt%3B%5C%2Fi%26gt%3B%20119%2C%20no.%205%20%28May%202015%29%3A%20654%26%23x2013%3B63.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.healthpol.2015.01.014%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.healthpol.2015.01.014%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Price%20elasticities%20in%20the%20German%20Statutory%20Health%20Insurance%20market%20before%20and%20after%20the%20health%20care%20reform%20of%202009%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%20B.%22%2C%22lastName%22%3A%22Pendzialek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marion%22%2C%22lastName%22%3A%22Danner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dusan%22%2C%22lastName%22%3A%22Simic%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Stock%22%7D%5D%2C%22abstractNote%22%3A%22This%20paper%20investigates%20the%20change%20in%20price%20elasticity%20of%20health%20insurance%20choice%20in%20Germany%20after%20a%20reform%20of%20health%20insurance%20contributions.%20Using%20a%20comprehensive%20data%20set%20of%20all%20sickness%20funds%20between%202004%20and%202013%2C%20price%20elasticities%20are%20calculated%20both%20before%20and%20after%20the%20reform%20for%20the%20entire%20market.%20The%20general%20price%20elasticity%20is%20found%20to%20be%20increased%20more%20than%204-fold%20from%20-0.81%20prior%20to%20the%20reform%20to%20-3.53%20after%20the%20reform.%20By%20introducing%20a%20new%20kind%20of%20health%20insurance%20contribution%20the%20reform%20seemingly%20increased%20the%20price%20elasticity%20of%20insured%20individuals%20to%20a%20more%20appropriate%20level%20under%20the%20given%20market%20parameters.%20However%2C%20further%20unintended%20consequences%20of%20the%20new%20contribution%20scheme%20were%20massive%20losses%20of%20market%20share%20for%20the%20more%20expensive%20sickness%20funds%20and%20therefore%20an%20undivided%20focus%20on%20pricing%20as%20the%20primary%20competitive%20element%20to%20the%20detriment%20of%20quality.%22%2C%22date%22%3A%222015-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.healthpol.2015.01.014%22%2C%22ISSN%22%3A%221872-6054%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%227ZDA33V6%22%5D%2C%22dateModified%22%3A%222024-03-11T12%3A22%3A09Z%22%7D%7D%2C%7B%22key%22%3A%22IB3MT8B7%22%2C%22library%22%3A%7B%22id%22%3A6298796%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Stock%20and%20Danner%22%2C%22parsedDate%22%3A%222014-02-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BStock%2C%20S.%2C%20and%20M.%20Danner.%20%26quot%3B%26lt%3Ba%20class%3D%26%23039%3Bzp-ItemURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00103-013-1895-y%26%23039%3B%26gt%3BKann%20die%20Erhebung%20von%20Einstellungen%20und%20Pr%5Cu00e4ferenzen%20die%20kleinr%5Cu00e4umige%20Versorgungsanalyse%20sinnvoll%20erg%5Cu00e4nzen%3F%26lt%3B%5C%2Fa%26gt%3B%26quot%3B%20%26lt%3Bi%26gt%3BBundesgesundheitsblatt%20-%20Gesundheitsforschung%20-%20Gesundheitsschutz%26lt%3B%5C%2Fi%26gt%3B%2057%2C%20no.%202%20%28February%201%2C%202014%29%3A%20188%5Cu201396.%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Kann%20die%20Erhebung%20von%20Einstellungen%20und%20Pr%5Cu00e4ferenzen%20die%20kleinr%5Cu00e4umige%20Versorgungsanalyse%20sinnvoll%20erg%5Cu00e4nzen%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Stock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Danner%22%7D%5D%2C%22abstractNote%22%3A%22Kleinr%5Cu00e4umige%20Versorgungsanalysen%20gewinnen%20vor%20dem%20Hintergrund%20regionaler%20Unterschiede%20in%20der%20Versorgung%20gesundheitspolitische%20Bedeutung.%20Die%20Kombination%20von%20Daten%20aus%20unterschiedlichen%20Quellen%20erm%5Cu00f6glicht%20es%2C%20struktur-%2C%20prozess-%20oder%20ergebnisbezogene%20Versorgungsvariation%20darzustellen%20und%20zu%20analysieren.%20Bei%20einer%20Variation%2C%20die%20nicht%20durch%20diese%20Daten%20erkl%5Cu00e4rt%20werden%20kann%2C%20k%5Cu00f6nnen%20die%20Einstellungen%2C%20Verhaltensweisen%20und%20Pr%5Cu00e4ferenzen%20der%20an%20der%20Versorgung%20ma%5Cu00dfgeblich%20beteiligten%20Akteure%2C%20insbesondere%20der%20%5Cu00c4rzte%20und%20Patienten%2C%20eine%20Rolle%20spielen.%20Im%20vorliegenden%20Beitrag%20wird%20skizziert%2C%20warum%20die%20Erhebung%20der%20Pr%5Cu00e4ferenzen%20dieser%20Akteure%20zur%20Erg%5Cu00e4nzung%20der%20kleinr%5Cu00e4umigen%20Versorgungsanalyse%20wichtig%20erscheint.%20Ihre%20Erhebung%20kann%20helfen%2C%20unerw%5Cu00fcnschte%20Versorgungsunterschiede%20zu%20erkl%5Cu00e4ren%20und%20zu%20verringern.%20Auf%20individueller%20Ebene%20kann%20dies%20beispielsweise%20bei%20der%20Inanspruchnahme-Entscheidung%2C%20die%20durch%20den%20Arzt%2C%20den%20Patienten%20bzw.%20beim%20%5Cu201eShared%20Decision%20Making%5Cu201c%20durch%20beide%20gemeinsam%20getroffen%20wird%2C%20geschehen.%20Auf%20aggregierter%20Ebene%20k%5Cu00f6nnen%20durch%20die%20Einbeziehung%20von%20Pr%5Cu00e4ferenzen%20bei%20der%20Erstellung%20von%20Leitlinien%20oder%20bei%20der%20Ausgestaltung%20neuer%20Versorgungsformen%20die%20Akzeptanz%20und%20durchg%5Cu00e4ngige%20Umsetzung%20dieser%20erh%5Cu00f6ht%20werden.%20Verschiedene%20Methoden%20zur%20Erhebung%20von%20Pr%5Cu00e4ferenzen%20werden%20vorgestellt%20und%20m%5Cu00f6gliche%20Anwendungsbereiche%20innerhalb%20der%20kleinr%5Cu00e4umigen%20Versorgungsanalyse%20aufgezeigt.%20Die%20Rolle%20von%20Einstellungen%20und%20Pr%5Cu00e4ferenzen%20zur%20Erkl%5Cu00e4rung%20von%20Versorgungsvariationen%20sollte%20gesundheitspolitisch%20aufgegriffen%20und%20es%20sollten%20Ma%5Cu00dfnahmen%20zu%20ihrer%20Einbeziehung%20in%20versorgungsrelevante%20Entscheidungsprozesse%20auf%20unterschiedlichen%20Ebenen%20unterst%5Cu00fctzt%20werden.%22%2C%22date%22%3A%222014-02-01%22%2C%22language%22%3A%22de%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00103-013-1895-y%22%2C%22ISSN%22%3A%221437-1588%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00103-013-1895-y%22%2C%22collections%22%3A%5B%2246NNKHWR%22%2C%22NPCAGTXX%22%2C%22X7PUUBWP%22%2C%22SPWXRLZV%22%2C%227ZDA33V6%22%5D%2C%22dateModified%22%3A%222025-05-18T08%3A06%3A51Z%22%7D%7D%5D%7D
Scheibler, Fülöp, Friedemann Geiger, Kai Wehkamp, Marion Danner, Marie Debrouwere, Constanze Stolz-Klingenberg, Anja Schuldt-Joswig, et al. “Patient-Reported Effects of Hospital-Wide Implementation of Shared Decision-Making at a University Medical Centre in Germany: A Pre-Post Trial.” BMJ Evidence-Based Medicine, November 24, 2023, bmjebm-2023-112462. https://doi.org/10.1136/bmjebm-2023-112462.
Danner, Marion, Marie Debrouwere, Anne Rummer, Kai Wehkamp, Jens Ulrich Rüffer, Friedemann Geiger, Robert Wolff, Karoline Weik, and Fueloep Scheibler. "A scattered landscape: assessment of the evidence base for 71 patient decision aids developed in a hospital setting." BMC Medical Informatics and Decision Making 22, no. 1 (February 17, 2022): 44.
Swift, Stephanie Louise, Thomas Puehler, Kate Misso, Shona Helen Lang, Carol Forbes, Jos Kleijnen, Marion Danner, et al. "Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients with severe aortic stenosis: a systematic review and meta-analysis." BMJ Open 11, no. 12 (December 1, 2021): e054222. https://doi.org/10.1136/bmjopen-2021-054222.
Debrouwere, Marie, Anne Rummer, Divna Tafelski, Corinna Knauff, Friedemann Geiger, Kai Wehkamp, Ulrich Rüffer, Fülöp Scheibler, and Marion Danner. “Wie gut ist die Studienlage für wichtige Behandlungsentscheidungen im Krankenhaus?,” Doc21ebmPS-4–10. German Medical Science GMS Publishing House, 2021. https://doi.org/10.3205/21ebm081.
Koldehoff, Andreas, Marion Danner, Daniele Civello, Kerstin Rhiem, Stephanie Stock, and Dirk Müller. "Cost-Effectiveness of Targeted Genetic Testing for Breast and Ovarian Cancer: A Systematic Review." Value in Health: The Journal of the International Society for Pharmacoeconomics and Outcomes Research 24, no. 2 (February 2021): 303–12. https://doi.org/10.1016/j.jval.2020.09.016.
Danner, Marion, Friedemann Geiger, Kai Wehkamp, Jens Ulrich Rueffer, Christine Kuch, Leonie Sundmacher, Tove Skjelbakken, et al. "Making shared decision-making (SDM) a reality: protocol of a large-scale long-term SDM implementation programme at a Northern German University Hospital." BMJ Open 10, no. 10 (October 1, 2020): e037575. https://doi.org/10.1136/bmjopen-2020-037575.
Müller, Dirk, Marion Danner, Rita Schmutzler, Christoph Engel, Kirsten Wassermann, Björn Stollenwerk, Stephanie Stock, and Kerstin Rhiem. "Economic modeling of risk-adapted screen-and-treat strategies in women at high risk for breast or ovarian cancer." The European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care 20, no. 5 (July 2019): 739–50. https://doi.org/10.1007/s10198-019-01038-1.
Müller, Dirk, Marion Danner, Kerstin Rhiem, Björn Stollenwerk, Christoph Engel, Linda Rasche, Lisa Borsi, Rita Schmutzler, and Stephanie Stock. “Cost-Effectiveness of Different Strategies to Prevent Breast and Ovarian Cancer in German Women with a BRCA 1 or 2 Mutation.” The European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care 19, no. 3 (April 2018): 341–53. https://doi.org/10.1007/s10198-017-0887-5.
Vennedey, Vera, Sonja Hm Derman, Mickaël Hiligsmann, Daniele Civello, Anja Schwalm, Astrid Seidl, Fülöp Scheibler, Stephanie Stock, Michael J. Noack, and Marion Danner. “Patients’ Preferences in Periodontal Disease Treatment Elicited alongside an IQWiG Benefit Assessment: A Feasibility Study.” Patient Preference and Adherence 12 (2018): 2437–47. https://doi.org/10.2147/PPA.S176067.
Bien, Daniela R., Marion Danner, Vera Vennedey, Daniele Civello, Silvia M. Evers, and Mickaël Hiligsmann. “Patients’ Preferences for Outcome, Process and Cost Attributes in Cancer Treatment: A Systematic Review of Discrete Choice Experiments.” The Patient 10, no. 5 (October 2017): 553–65. https://doi.org/10.1007/s40271-017-0235-y.
Danner, Marion, Vera Vennedey, Mickaël Hiligsmann, Sascha Fauser, Christian Gross, and Stephanie Stock. “Comparing Analytic Hierarchy Process and Discrete-Choice Experiment to Elicit Patient Preferences for Treatment Characteristics in Age-Related Macular Degeneration.” Value in Health: The Journal of the International Society for Pharmacoeconomics and Outcomes Research 20, no. 8 (September 2017): 1166–73. https://doi.org/10.1016/j.jval.2017.04.022.
Danner, Marion, Vera Vennedey, Mickaël Hiligsmann, Sascha Fauser, and Stephanie Stock. “Focus Groups in Elderly Ophthalmologic Patients: Setting the Stage for Quantitative Preference Elicitation.” The Patient 9, no. 1 (February 2016): 47–57. https://doi.org/10.1007/s40271-015-0122-3.
Danner, Marion, Vera Vennedey, Mickaël Hiligsmann, Sascha Fauser, Christian Gross, and Stephanie Stock. "How Well Can Analytic Hierarchy Process be Used to Elicit Individual Preferences? Insights from a Survey in Patients Suffering from Age-Related Macular Degeneration." The Patient - Patient-Centered Outcomes Research 9, no. 5 (2016): 481–92. https://doi.org/10.1007/s40271-016-0179-7.
Vennedey, Vera, Marion Danner, Silvia Maa Evers, Sascha Fauser, Stephanie Stock, Carmen D. Dirksen, and Mickaël Hiligsmann. “Using Qualitative Research to Facilitate the Interpretation of Quantitative Results from a Discrete Choice Experiment: Insights from a Survey in Elderly Ophthalmologic Patients.” Patient Preference and Adherence 10 (2016): 993–1002. https://doi.org/10.2147/PPA.S101584.
Pendzialek, Jonas B., Marion Danner, Dusan Simic, and Stephanie Stock. “Price Elasticities in the German Statutory Health Insurance Market before and after the Health Care Reform of 2009.” Health Policy (Amsterdam, Netherlands) 119, no. 5 (May 2015): 654–63. https://doi.org/10.1016/j.healthpol.2015.01.014.
Stock, S., and M. Danner. "Kann die Erhebung von Einstellungen und Präferenzen die kleinräumige Versorgungsanalyse sinnvoll ergänzen?" Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 57, no. 2 (February 1, 2014): 188–96.